Spider mites and thrips hit CBD plants just as readily as any other cannabis, and spraying synthetic pesticides on flower you intend to consume is a bad idea. Neem early in veg, predatory mites and simple sticky traps cover most situations. The integrated pest management page on https://calmcbdseeds.com lists which treatments are safe up to which week of flower, which is the detail most general guides skip. Stopping all sprays three weeks before harvest keeps residue out of the final product.